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INNOVATIVE APPROACHES TO BIOMATERIALS’ TECHNOLOGY THROUGH SYSTEMATIC SPECTROSCOPIC ANALYSES
http://hdl.handle.net/10212/2522
http://hdl.handle.net/10212/2522a3cd52eb-98a4-4513-b648-8b5ec190a4bb
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内容の要約 (5.4 MB)
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内容・審査結果の要旨 (170.0 KB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2022-04-16 | |||||||||
| タイトル | ||||||||||
| タイトル | INNOVATIVE APPROACHES TO BIOMATERIALS’ TECHNOLOGY THROUGH SYSTEMATIC SPECTROSCOPIC ANALYSES | |||||||||
| 言語 | en | |||||||||
| その他のタイトル | ||||||||||
| その他のタイトル | 組織的分光分析評価における最先端生体材料への革新的アプローチ | |||||||||
| 言語 | ja | |||||||||
| 作成者 |
ロンディネッラ, アルフレド
× ロンディネッラ, アルフレド
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| アクセス権 | ||||||||||
| アクセス権 | open access | |||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | ALUMINA | |||||||||
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| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | ZIRCONIA | |||||||||
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| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | SILICON NITRIDE | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | ZIRCONIA-TOUGHENED ALUMINA | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | LOW-TEMPERATURE DEGRADATION | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | UHMWPE | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | OXYDATION | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | COMPUTER-AIDED DESIGN | |||||||||
| 主題 | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | METAL CONTAMINATION | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | The incidence of total hip arthroplasty (THA) has increased over the last decades, as a consequence of increasing of human average lifetime and changing in our habits and lifestyle. As people live longer, their bones become gradually brittler and the probability of incurring in traumatic events (such as dislocation or fracture) or developing arthritis increases. Furthermore, obesity has become a non-negligible problem in most of the First World countries. About 13% of the world adult population (about 650 million people) were obese in 2016, 11% of men and 15% of women. The only reasonable option to maintain mobility and to avoid chronic pain is often surgery. A major fraction of the people undergoing THA will surely outlive the expected service time of an artificial hip-joint (about 15-20 years for a successful surgery). Understanding degradation phenomena occurring inside the components of an artificial hipjoint can be of utmost importance to reduce costs related to revision surgeries and improve patient’s life. However, predictions do not always provide reliable outcomes because the intricate complexity of in-vivo phenomena are hard to reproduce and neither in-vitro tests nor finite elements simulations have been able, so far, to match reality. In the first part of this thesis, laser and electronic spectroscopy have been combined with several spectroscopic techniques (among which Raman micro-probe spectroscopy, X-ray photoelectron spectroscopy, Fourier-Transformed infrared spectroscopy etc.) to investigate degradation phenomena occurring on the ceramic femoral head and the polymeric acetabular cup; two of the most important components of an artificial hip joint. Zirconia Toughened Alumina (ZTA) retrieved femoral heads were investigated in-toto through a new automated protocol to obtain information about the the chemical, crystallographic, and micromechanical phenomena occurring in-vivo, pointing out a severe crystallographic instability. These information have been used, subsequently, to rationalize the discrepancy between predicted and in-vivo data. While current hydrothermal tests address only one of the possible triggers contributing to ZTA surface degradation, it has been found that transitional metal contamination accelerates the kinetics of such phenomena. Subsequently we focused on ceramics and polymer surface chemistry to understand sliding behavior of common bearings in artificial hip joints. In particular we focused on UHMWPE wear behavior against ZTA and compared it with a promising alternative non-oxide material, silicon nitride (Si3N4). Contrary to common knowledge, oxide-based ceramics are not completely bioinert. In fact, its tribologic behavior causes oxygen ions to be released from Al2O3 surfaces which, in turn, accelerate oxidative degradation in UHMWPE. On the other hand, silicon nitride scavenges oxygen from the tribolayer instead of releasing | |||||||||
| 言語 | en | |||||||||
| 日付 | ||||||||||
| 日付 | 2019-03-25 | |||||||||
| 日付タイプ | Issued | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
| 資源タイプ | doctoral thesis | |||||||||
| 学位授与番号 | ||||||||||
| 学位授与番号 | 甲第912号 | |||||||||
| 学位名 | ||||||||||
| 言語 | ja | |||||||||
| 学位名 | 博士（工学） | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2019-03-25 | |||||||||
| 学位授与機関 | ||||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||||
| 学位授与機関識別子 | 14303 | |||||||||
| 言語 | ja | |||||||||
| 学位授与機関名 | 京都工芸繊維大学 | |||||||||
